NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Sample Answer for NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT Included After Question

Discuss the ethical guidelines that would need to be implemented when conducting translational research. What are the ethical and legal considerations related to translating research into practice? Discuss what steps you would take as a member of a translational research team in order to establish ethical guidelines for conducting translational research.

A Sample Answer For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Description: NUR 550 Topic 3 DQ 1

PICOT (Population/Problem, Intervention, Comparison, Outcome, and Time to achieve the outcome) is a method that helps clarify the qualities needed to create a good question out of a practice issue or problem affecting a population of focus.

The purpose of this assignment is to complete your PICOT for your selected nursing practice problem. Refer to your “Evidence-Based Practice Project Proposal: Identification of Nursing Practice Problem” assignment from Topic 1 to complete this assignment. If your nursing practice problem or PICOT required revision, include those revisions in this assignment. The final PICOT you develop in this assignment will provide the framework for developing your evidence-based practice project proposal. Use the “PICOT-Final” template to complete this assignment.NUR 550 Topic 3 DQ 1

Refer to the “Evidence-Based Practice Project Proposal – Assignment Overview” document for an overview of the evidence-based practice project proposal assignments.NUR 550 Topic 3 DQ 1

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You are required to cite at least four peer-reviewed sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.NUR 550 Topic 3 DQ 1

You are not required to submit this assignment to LopesWrite.

Topic 3 DQ 1

Description:

NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

NUR 550 Evidence-Based Practice Project Proposal PICOT

Discuss the ethical guidelines that would need to be implemented when conducting translational research. What are the ethical and legal considerations related to translating research into practice? Discuss what steps you would take as a member of a translational research team in order to establish ethical guidelines for conducting translational research

Description: NUR 550 Topic 3 DQ 1

PICOT (Population/Problem, Intervention, Comparison, Outcome, and Time to achieve the outcome) is a method that helps clarify the qualities needed to create a good question out of a practice issue or problem affecting a population of focus.

The purpose of this assignment is to complete your PICOT for your selected nursing practice problem. Refer to your “Evidence-Based Practice Project Proposal: Identification of Nursing Practice Problem” assignment from Topic 1 to complete this assignment. If your nursing practice problem or PICOT required revision, include those revisions in this assignment. The final PICOT you develop in this assignment will provide the framework for developing your evidence-based practice project proposal. Use the “PICOT-Final” template to complete this assignment.NUR 550 Topic 3 DQ 1

Refer to the “Evidence-Based Practice Project Proposal – Assignment Overview” document for an overview of the evidence-based practice project proposal assignments.NUR 550 Topic 3 DQ 1

You are required to cite at least four peer-reviewed sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.NUR 550 Topic 3 DQ 1

You are not required to submit this assignment to LopesWrite.

Topic 3 DQ 1

Description:

Discuss the ethical guidelines that would need to be implemented when conducting translational research. What are the ethical and legal considerations related to translating research into practice? Discuss what steps you would take as a member of a translational research team in order to establish ethical guidelines for conducting translational research.

A Sample Answer 2 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

When conducting translational research, it is important to consider the five ethical principles that provided the ethical foundation for nursing, which are beneficence, nonmaleficence, autonomy, justice, and the principle of fidelity (Melnyk & Fineout-Overholt, 2023). Moreover, there are ethical requirements specifically related to clinical research, including social or scientific value, scientific validity, fair subject selection, favorable risk-benefit ratio, independent review, respect for participants, and informed consent (Melnyk & Fineout-Overholt, 2023). Nonetheless, translational research can conflict with these ethical principles under the following circumstances: “attempts to improve quality for some patients inadvertently cause harm for others… strategies intended to improve quality that may turn out to be ineffective or even lower the quality of care… activities declared to be quality improvement (QI) that may be more accurately described as clinical research or vice versa” (Melnyk & Fineout-Overholt, 2023, p. 683).  

From a legal standpoint, there are regulations that researchers must consider. This includes the approval of research involving humans as set forth by the Department of Health and Human Services (Clinical and Translational Science Collaborative [CTSC], 2024). The Food and Drug Administration (FDA) also has several regulations that researchers must follow for the protection of participants and patients (CTSC, 2024). This is all in addition to local regulations and policies set forth by lawmakers that all researchers must obey when conducting research and translating such research into practice.  

When proposing a translational research study, I would ensure that the research is independently reviewed by an ethics committee or institutional review board (IRB). An IRB is especially important in research as it reviews studies and safeguards participants (Melnyk & Fineout-Overholt, 2023). IRB approval is essential prior to beginning a study with human subject. Additionally, as a member of a translational research team, I would ensure that I am sincerely and intentionally adhering to ethical principles related to research (as listed above). I would continue to review these principles throughout the research process to better ensure that the team is not straying from them and is conducting the study with the utmost integrity and best intentions to advance health outcomes. 

Topic 3 Participation

Description:

NA

Topic 3: Translational Research Framework and Legal and Ethical Considerations

Description

Objectives:

  1. Discuss ethical guidelines for conducting translational research.
    2. Examine ethical considerations related to translating research into practice .
    3. Examine legal considerations related to translating research into practice.
    4. Discuss ethical research considerations specific to population health.
    Study Materials

Advanced Practice Nursing: Essential Knowledge for the Profession

Click here to ORDER an A++ paper from our Verified MASTERS and DOCTORATE WRITERS: NUR 550 Evidence-Based Practice Project Proposal PICOT

Description:

Read Chapter 26 in Advanced Practice Nursing: Essential Knowledge for the Profession.

Population Health: Creating a Culture of Wellness

Description: NUR 550 Topic 3 DQ 1

Read Chapter 10 in Population Health: Creating a Culture of Wellness.

A Few Ethical Issues in Translation Research for Gene and Cell Therapy

Description: NUR 550 Topic 3 DQ 1

Read “A Few Ethical Issues in Translation Research for Gene and Cell Therapy,” by Riva and Petrini, from Journal of Translational Medicine (2019).

The Underappreciated and Misunderstood PICOT Question: A Critical Step in EBP Process

Description:

Read “The Underappreciated and Misunderstood PICOT Question: A Critical Step in EBP Process,” by Gallagher-Ford and Melnyk, from Worldviews on Evidence-Based Nursing (2019).

Life After PICOT: Taking the Next Step in a Clinical Inquiry Project

Description: NUR 550 Topic 3 DQ 1

Read “Life After PICOT: Taking the Next Step in a Clinical Inquiry Project,” by Granger, from AACN Advanced Critical Care (2020).

A Sample Answer 3 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

The value of biostatistics in population health research is the ability to discover aspects of a particular population and their factors of health (Minkoff, 2022). According to Minkoff (2022), biostatistics is the “application of statistical concepts to biology and medicine in order to summarize the characteristics of a sample and test predictions”. Biostatistics allows for new information to be discovered in a sample size of a population and then utilized for the benefit of a larger group related to the sample size tested. This is valuable because it uses the results of a small amount of people to make predictions on how it can affect a larger amount of people. An example of this would be conducting a study on gestational diabetic patients that delivery at one local hospital in the span of 6 months. Those results could be used as a possible predictor for various other studies in the same patient population in other places. 

According to the Centers of Disease Control and Prevention, epidemiology is “the study of distribution and determinants of health-related states and events in a specific population” (Centers for Disease Control and Prevention, 2016). Population health can be defined as the health outcomes of a particular group (Garmon, 2017). The role of epidemiology in researching and addressing population health challenges is critical. This is because the two are correlated in research.  As research is done on the health of a particular population, the epidemiology also has to be looked at in the community of that population. For example, according to Nash et al. (2019), health systems now have the obligation and responsibility to look at the health of the community they serve rather than just the individual they are treating. This includes performing health assessments and implementing programs in the communities for health promotion and disease prevention (Nash et al., 2019). Epidemiology addresses the health challenges and outcomes that a population might face.

Both epidemiology and biostatistics are significant to my evidence-based proposal because both should be used to gather meaningful results or outcomes. The ability to study a small group of post-op 1st time cesarean sections patients can provide a foundation or prediction on the larger population of post-op 1st time cesarean section patients in other areas. By taking the results from that study it can be compared to other studies in different populations and regions. This incorporates both biostatistics and epidemiology in my proposal.

Description: NUR 550 Topic 3 DQ 1

Read “The Belmont Report,” by The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, located on the U.S. Department of Health and Human Services website (1979).

PICO: A Model for Evidence-Based Research

Description:

View “PICO: A Model for Evidence-Based Research,” by Binghamton University Libraries, located on YouTube (2017).

What is Evidence-Based Practice?

Description: NUR 550 Topic 3 DQ 1

View “What is Evidence-Based Practice?” by Lippincott NursingCenter.com, located on YouTube (2016).

Course Code Class Code Assignment Title Total Points
NUR-550 NUR-550-O503 Evidence-Based Practice Project Proposal: PICOT 75.0

Criteria Percentage Unsatisfactory (0.00%) Less Than Satisfactory (80.00%) Satisfactory (88.00%) Blank (92.00%) Blank (100.00%)
Content 100.0%
Population (Revision) 7.0% The population is not described, or the required revisions were not made for the population description. NA Revisions were made accordingly for the population description, but some information or detail is needed for accuracy or clarity. NA The population is thoroughly and accurately described. No revision was needed.NUR 550 Topic 3 DQ 1

Intervention (Revision) 8.0% The proposed intervention is not described, or the required revisions were not made for the described intervention. NA Revisions were made accordingly for the proposed intervention, but some information or detail is needed for accuracy or clarity. NA The proposed intervention is clearly described and relevant to the nursing practice problem and population. No revision was needed.

Comparison 10.0% A description of the comparison information is not included. A description of the comparison information is incomplete or incorrect. A description of the comparison information is included but lacks evidence and measurable outcomes. A description of the comparison information is complete and includes sufficient evidence and measurable outcomes. A description of the comparison information is extremely thorough with substantial evidence and measurable outcomes.NUR 550 Topic 3 DQ 1

Outcome 10.0% A description of the outcome is not included. A description of the outcome is not included. A description of the outcome is included but lacks evidence. A description of the outcome is complete and includes sufficient evidence. A description of the outcome is extremely thorough with substantial evidence

Timeline 10.0% A description of the timeline is not included. A description of the timeline is incomplete or incorrect. A description of the timeline is included but lacks evidence. A description of the timelines is complete and includes sufficient evidence. A description of the timeline is extremely thorough with substantial evidence.

PICOT 20.0% The PICOT statement is omitted. The PICOT statement is incomplete. The PICOT statement is presented but there some inaccuracies. The PICOT statement is presented. Some detail is needed. The PICOT statement concisely and accurately describes the problem.NUR 550 Topic 3 DQ 1

Problem Statement 20.0% A problem statement is not included. The problem statement is incomplete. The problem statement is generally presented. There are some inaccuracies. More support is needed to justify or rationalize the problem. The problem statement is presented. Adequate support is provided to justify or rationalize the problem. The problem statement concisely describes the issue using strong support to rationalize and justify the problem.

Required Sources 5.0% Sources are not included. Number of required sources is only partially met. Number of required sources is met, but sources are outdated or inappropriate. Number of required sources is met. Sources are current, but not all sources are appropriate for the assignment criteria and nursing content. Number of required resources is met. Sources are current and appropriate for the assignment criteria and nursing content.NUR 550 Topic 3 DQ 1NUR 550 Topic 3 DQ 1

Mechanics of Writing (includes spelling, punctuation, grammar, and language use) 5.0% Surface errors are pervasive enough that they impede communication of meaning. Inappropriate word choice or sentence construction is employed. Frequent and repetitive mechanical errors distract the reader. Inconsistencies in language choice (register) or word choice are present.

Sentence structure is correct but not varied. Some mechanical errors or typos are present, but they are not overly distracting to the reader. Correct and varied sentence structure and audience-appropriate language are employed. Prose is largely free of mechanical errors, although a few may be present. The writer uses a variety of effective sentence structures and figures of speech. The writer is clearly in command of standard, written, academic English.

Documentation of Sources (citations, footnotes, references, bibliography, etc., as appropriate to assignment and style) 5.0% Sources are not documented. Documentation of sources is inconsistent or incorrect, as appropriate to assignment and style, with numerous formatting errors. Sources are documented, as appropriate to assignment and style, although some formatting errors may be present.NUR 550 Topic 3 DQ 1

Sources are documented, as appropriate to assignment and style, and format is mostly correct. Sources are completely and correctly documented, as appropriate to assignment and style, and format is free of error.

I think that the ethical guidelines for conducting translational research are similar to other research with a few extra considerations. The reason there needs to be extra consideration is because real people are being put through translational research. The things being studied have a goal of becoming the evidence-based standard used at bedside on real people. Some of these ethical principles are beneficence, non-maleficence, autonomy, justice, and privacy. Additionally, before any research is performed informed consent needs to be completed.NUR 550 Topic 3 DQ 1

All participants in any setting need to be told all of the risks and benefits before making a decision to protect both the participant and the researcher.NUR 550 Topic 3 DQ 1

As a member of the translational research team, some of the steps I would take to establish ethical guidelines for conduction research is making sure that the benefits outweigh the risk of the study. As well as making sure the participants are appropriate for the research. Making sure that the study is safe is I think the most important thing.NUR 550 Topic 3 DQ 1

If the benefits do not outweigh the risk, then the study does not need to be completed. If you do not have proper participants than the study will not be good. Research safety is a broad concept that applies to work performed inside the lab and outside the lab (University of Michigan, 2022).

Luckily certain aspects of research safety are governed by federal and state regulations that prescribe the oversight functions however, achieving a safe research environment requires the conscientious effort from everyone who is involved in the study (University of Michigan, 2022).NUR 550 Topic 3 DQ 1

 

 

References NUR 550 Topic 3 DQ 1

University of Michigan. (2022, December 1). Research Safety. Research Ethics and Compliance. https://research-compliance.umich.edu/research-safety

A Sample Answer 4 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

As with any type of research, gaining appropriate informed consent is a top priority and issue.  Since from the initial stages of a study, translational research is done directly on patients in the clinical setting instead of a laboratory, it is vitally important to insure that the individuals being studied have had the opportunity to be made aware of the conditions of the study, and the ability to accept or reject them without it negatively affecting the care that they receive.NUR 550 Topic 3 DQ 1

Gaining voluntary informed consent on patients that have a decreased level of consciousness, are in need of emergency assistance, are suffering from intense pain, or are critically ill presents unique challenges. (Gupta, 2022) Unfortunately, throughout history there are multiple instances where research studies were conducted on people with no regard to their human life or their dignity.NUR 550 Topic 3 DQ 1

It is imperative that regulatory laws and rules like the Nuremberg Code and the Common Rule be followed to avoid legal, ethical and moral violations while performing translational research studies. (Gupta, 2022)NUR 550 Topic 3 DQ 1

Reference: NUR 550 Topic 3 DQ 1

Gupta, N. (2022). Ethical considerations in translational research. In H. Prabhakar, C. Mahajan & I. Kapoor (Eds.), Perioperative Neuroscience (pp. 215-228). Academic Press. https://doi.org/10.1016/B978-0-323-91003-3.00004-0

A Sample Answer 5 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Translational research is performed with the aim of significantly impacting on population health outcomes. As such the consequences are dire if the researchers do not adhere to ethical guidelines. As healthcare practitioners, we have a moral obligation of doing no harm and the same applies to researchers. When conducting research studies research have to respect the rights and privacy of the participants.NUR 550 Topic 3 DQ 1

The ethical principles of beneficence, non-maleficence, autonomy and justice must also be considered. These guidelines offer a direction and baseline for how legal and ethical considerations should be followed when putting translational research into practice.

Translational research must make sure that the interventions used cause the participants the least amount of harm. Any research that has a high risk of injury without taking the required precautions is seen as unethical and may have legal repercussions. (Gupta, 2022) The translational researchers must also guarantee that participation is voluntarily given and that subjects have given their consent after being fully informed.NUR 550 Topic 3 DQ 1

It is unethical to conduct research without telling the participants about it. Maintaining patient confidentiality and anonymity in line with HIPAA rules and regulations is another factor to take into account.

As a member of the translational research team, some of the actions I would take to set ethical standards for carrying out translational research include notifying the team members about the pertinent research guidelines involved in carrying out such research. In addition, I would make sure that every research participant was recognized and duly informed of the ongoing translational research and their responsibilities in it.

I would also promote periodic reviews to determine whether the legal and ethical standards governing translational research are being followed.NUR 550 Topic 3 DQ 1

Respecting study participants involves valuing their autonomy—their independence and capacity to decide for themselves without interference from others (Steel, 2019). Based on the written and verbal facts supplied to them through an informed consent process, they should be free to decide whether or not to engage in research.

References NUR 550 Topic 3 DQ 1

Gupta, N. (2022). Ethical considerations in Translational Research. Perioperative Neuroscience, 215–228. https://doi.org/10.1016/b978-0-323-91003-3.00004-0

Steel, R. (2019). Reconceptualizing risk–benefit analyses: The case of hiv cure research. Journal of Medical Ethics, 46(3), 212–219. https://doi.org/10.1136/medethics-2019-105548

Discuss the ethical guidelines that would need to be implemented when conducting translational research. What are the ethical and legal considerations related to translating research into practice? Discuss what steps you would take as a member of a translational research team in order to establish ethical guidelines for conducting translational research.

Topic 3 Participation NUR 550 Topic 3 DQ 1

Description:

NA

Topic 3: Translational Research Framework and Legal and Ethical Considerations

Description NUR 550 Topic 3 DQ 1

Objectives:

  1. Discuss ethical guidelines for conducting translational research.
    2. Examine ethical considerations related to translating research into practice .
    3. Examine legal considerations related to translating research into practice.
    4. Discuss ethical research considerations specific to population health.
    Study Materials

Advanced Practice Nursing: Essential Knowledge for the Profession

Click here to ORDER an A++ paper from our Verified MASTERS and DOCTORATE WRITERS: NUR 550 Evidence-Based Practice Project Proposal PICOT

Description:

Read Chapter 26 in Advanced Practice Nursing: Essential Knowledge for the Profession.

Population Health: Creating a Culture of Wellness

Description:

Read Chapter 10 in Population Health: Creating a Culture of Wellness.

A Few Ethical Issues in Translation Research for Gene and Cell Therapy

Description:

Read “A Few Ethical Issues in Translation Research for Gene and Cell Therapy,” by Riva and Petrini, from Journal of Translational Medicine (2019).

The Underappreciated and Misunderstood PICOT Question: A Critical Step in EBP Process

Description:

Read “The Underappreciated and Misunderstood PICOT Question: A Critical Step in EBP Process,” by Gallagher-Ford and Melnyk, from Worldviews on Evidence-Based Nursing (2019).

Life After PICOT: Taking the Next Step in a Clinical Inquiry Project

Description:

Read “Life After PICOT: Taking the Next Step in a Clinical Inquiry Project,” by Granger, from AACN Advanced Critical Care (2020).

The Belmont Report

Description:

Read “The Belmont Report,” by The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, located on the U.S. Department of Health and Human Services website (1979).

PICO: A Model for Evidence-Based Research

Description:

View “PICO: A Model for Evidence-Based Research,” by Binghamton University Libraries, located on YouTube (2017).

What is Evidence-Based Practice?

Description:

View “What is Evidence-Based Practice?” by Lippincott NursingCenter.com, located on YouTube (2016).

Course Code Class Code Assignment Title Total Points
NUR-550 NUR-550-O503 Evidence-Based Practice Project Proposal: PICOT 75.0

Criteria Percentage Unsatisfactory (0.00%) Less Than Satisfactory (80.00%) Satisfactory (88.00%) Blank (92.00%) Blank (100.00%)
Content 100.0%
Population (Revision) 7.0% The population is not described, or the required revisions were not made for the population description. NA Revisions were made accordingly for the population description, but some information or detail is needed for accuracy or clarity. NA The population is thoroughly and accurately described. No revision was needed.

Intervention (Revision) 8.0% The proposed intervention is not described, or the required revisions were not made for the described intervention. NA Revisions were made accordingly for the proposed intervention, but some information or detail is needed for accuracy or clarity. NA The proposed intervention is clearly described and relevant to the nursing practice problem and population. No revision was needed.

Comparison 10.0% A description of the comparison information is not included. A description of the comparison information is incomplete or incorrect. A description of the comparison information is included but lacks evidence and measurable outcomes. A description of the comparison information is complete and includes sufficient evidence and measurable outcomes. A description of the comparison information is extremely thorough with substantial evidence and measurable outcomes.

Outcome 10.0% A description of the outcome is not included. A description of the outcome is not included. A description of the outcome is included but lacks evidence. A description of the outcome is complete and includes sufficient evidence. A description of the outcome is extremely thorough with substantial evidence

Timeline 10.0% A description of the timeline is not included. A description of the timeline is incomplete or incorrect. A description of the timeline is included but lacks evidence. A description of the timelines is complete and includes sufficient evidence. A description of the timeline is extremely thorough with substantial evidence.

PICOT 20.0% The PICOT statement is omitted. The PICOT statement is incomplete. The PICOT statement is presented but there some inaccuracies. The PICOT statement is presented. Some detail is needed. The PICOT statement concisely and accurately describes the problem.

Problem Statement 20.0% A problem statement is not included. The problem statement is incomplete. The problem statement is generally presented. There are some inaccuracies. More support is needed to justify or rationalize the problem. The problem statement is presented. Adequate support is provided to justify or rationalize the problem. The problem statement concisely describes the issue using strong support to rationalize and justify the problem.

Required Sources 5.0% Sources are not included. Number of required sources is only partially met. Number of required sources is met, but sources are outdated or inappropriate. Number of required sources is met. Sources are current, but not all sources are appropriate for the assignment criteria and nursing content. Number of required resources is met. Sources are current and appropriate for the assignment criteria and nursing content.

Mechanics of Writing (includes spelling, punctuation, grammar, and language use) 5.0% Surface errors are pervasive enough that they impede communication of meaning. Inappropriate word choice or sentence construction is employed. Frequent and repetitive mechanical errors distract the reader. Inconsistencies in language choice (register) or word choice are present.

Sentence structure is correct but not varied. Some mechanical errors or typos are present, but they are not overly distracting to the reader. Correct and varied sentence structure and audience-appropriate language are employed. Prose is largely free of mechanical errors, although a few may be present. The writer uses a variety of effective sentence structures and figures of speech. The writer is clearly in command of standard, written, academic English.

Documentation of Sources (citations, footnotes, references, bibliography, etc., as appropriate to assignment and style) 5.0% Sources are not documented. Documentation of sources is inconsistent or incorrect, as appropriate to assignment and style, with numerous formatting errors. Sources are documented, as appropriate to assignment and style, although some formatting errors may be present.

Sources are documented, as appropriate to assignment and style, and format is mostly correct. Sources are completely and correctly documented, as appropriate to assignment and style, and format is free of error.

A Sample Answer 6 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

I think that the ethical guidelines for conducting translational research are similar to other research with a few extra considerations. The reason there needs to be extra consideration is because real people are being put through translational research. The things being studied have a goal of becoming the evidence-based standard used at bedside on real people. Some of these ethical principles are beneficence, non-maleficence, autonomy, justice, and privacy. Additionally, before any research is performed informed consent needs to be completed.

All participants in any setting need to be told all of the risks and benefits before making a decision to protect both the participant and the researcher.

As a member of the translational research team, some of the steps I would take to establish ethical guidelines for conduction research is making sure that the benefits outweigh the risk of the study. As well as making sure the participants are appropriate for the research. Making sure that the study is safe is I think the most important thing.

If the benefits do not outweigh the risk, then the study does not need to be completed. If you do not have proper participants than the study will not be good. Research safety is a broad concept that applies to work performed inside the lab and outside the lab (University of Michigan, 2022).

Luckily certain aspects of research safety are governed by federal and state regulations that prescribe the oversight functions however, achieving a safe research environment requires the conscientious effort from everyone who is involved in the study (University of Michigan, 2022).

NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT References

University of Michigan. (2022, December 1). Research Safety. Research Ethics and Compliance. https://research-compliance.umich.edu/research-safety

A Sample Answer 7 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

As with any type of research, gaining appropriate informed consent is a top priority and issue.  Since from the initial stages of a study, translational research is done directly on patients in the clinical setting instead of a laboratory, it is vitally important to insure that the individuals being studied have had the opportunity to be made aware of the conditions of the study, and the ability to accept or reject them without it negatively affecting the care that they receive.

Gaining voluntary informed consent on patients that have a decreased level of consciousness, are in need of emergency assistance, are suffering from intense pain, or are critically ill presents unique challenges. (Gupta, 2022) Unfortunately, throughout history there are multiple instances where research studies were conducted on people with no regard to their human life or their dignity.

It is imperative that regulatory laws and rules like the Nuremberg Code and the Common Rule be followed to avoid legal, ethical and moral violations while performing translational research studies. (Gupta, 2022)

NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT Reference:

Gupta, N. (2022). Ethical considerations in translational research. In H. Prabhakar, C. Mahajan & I. Kapoor (Eds.), Perioperative Neuroscience (pp. 215-228). Academic Press. https://doi.org/10.1016/B978-0-323-91003-3.00004-0

A Sample Answer 8 For the Assignment: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Title: NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT

Translational research is performed with the aim of significantly impacting on population health outcomes. As such the consequences are dire if the researchers do not adhere to ethical guidelines. As healthcare practitioners, we have a moral obligation of doing no harm and the same applies to researchers. When conducting research studies research have to respect the rights and privacy of the participants.

The ethical principles of beneficence, non-maleficence, autonomy and justice must also be considered. These guidelines offer a direction and baseline for how legal and ethical considerations should be followed when putting translational research into practice.

Translational research must make sure that the interventions used cause the participants the least amount of harm. Any research that has a high risk of injury without taking the required precautions is seen as unethical and may have legal repercussions. (Gupta, 2022) The translational researchers must also guarantee that participation is voluntarily given and that subjects have given their consent after being fully informed.

It is unethical to conduct research without telling the participants about it. Maintaining patient confidentiality and anonymity in line with HIPAA rules and regulations is another factor to take into account.

As a member of the translational research team, some of the actions I would take to set ethical standards for carrying out translational research include notifying the team members about the pertinent research guidelines involved in carrying out such research. In addition, I would make sure that every research participant was recognized and duly informed of the ongoing translational research and their responsibilities in it.

I would also promote periodic reviews to determine whether the legal and ethical standards governing translational research are being followed.

Respecting study participants involves valuing their autonomy—their independence and capacity to decide for themselves without interference from others (Steel, 2019). Based on the written and verbal facts supplied to them through an informed consent process, they should be free to decide whether or not to engage in research.

NUR 550 Topic 3 DQ 1 Evidence-Based Practice Project Proposal PICOT References

Gupta, N. (2022). Ethical considerations in Translational Research. Perioperative Neuroscience, 215–228. https://doi.org/10.1016/b978-0-323-91003-3.00004-0

Steel, R. (2019). Reconceptualizing risk–benefit analyses: The case of hiv cure research. Journal of Medical Ethics, 46(3), 212–219. https://doi.org/10.1136/medethics-2019-105548

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